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Samples were mixed by vortexing and incubated for 10 min 4 C with rotation, before centrifugation (10 min, 1,000 g , 4 C)

IL-1 Induces pathologically activated osteoclasts bearing extremely high levels of resorbing activity: A possible pathological subpopulation of osteoclasts, accompanied by suppressed expression of kindlin-3 and talin-1

Similar content being viewed by others Introduction Pentadecapeptide BPC 157 is known to possess therapeutic efficacy on variable tissue healing and angiogenesis that is considered through the activation of nitric oxide system as reported in previous studies 1,2,3,4,5,6