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Modulation of immune and non-immune cell metabolism The effects of mycoplasmas on the immune system are well established and include effects on differentiation and activation of innate immunity cells (macrophages, dentritic cells, neutrophils, NK) and on adaptive immunity cells (T and B cells)

Nanoparticle-based delivery systems The therapeutic application of PRLMs in chronic inflammatory diseases is limited by their restricted tissue-targeting capacity

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The practical reality: IV therapy requires clinic visits, carries needle stick risks, and costs far more than oral options