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The spontaneously beating hearts were then rinsed by immersion in icecold KrebsHenseleit Buffer (118 mmol/L NaCl, 4.7 mmol/L KCl, 1.2 mmol/L KH 2 PO 4 , 1.2 mmol/L MgSO 4 , 3.0 mmol/L CaCl 2 , 25 mmol/L NaHCO 3 , 11 mmol/L glucose, and 0.5 mmol/L EDTA, pH 7.4) (SigmaAldrich, Munich, Germany), and cannulated by the aorta on the Langendorff system (EMKA Technologies, Paris, France)

Gene Ontology analysis (GO) of these DEGs further revealed significant enrichment of terms associated with plant defense signaling, including defense response, cellular responses to JA, response to wounding, and response to hormone (Fig

Evidence is mounting that KPV is strongly anti-inflammatory, immune-modulating, wound healing, and antimicrobial

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