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In young rats exposed to lead or arsenic, MiADMSA was found to potentiate the synthesis of metallothionine in liver and kidneys and glutathione in liver and brain, along with significantly reducing the glutathione disulfide levels in tissues

In addition to its culinary utility, black pepper also possesses medicinal activities such as anti-cancer, anti-inflammatory, analgesic, anticonvulsant, anti-ulcer, antioxidant, cytoprotective and anti-depressant effects (Butt et al., 2013)
In the aging mouse brain, there is an increase in lactate caused by diminished pyruvate flux through the citric acid cycle [288]
