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107 Critical oncogenic signaling proteins such as EGFR, HER2, AKT, and BCR-ABL rely on HSP90 for stability and function

In addition, it significantly reduced transcriptional programs involved in steroid and bile acid synthesis, which in turn reduced androgen synthesis and inhibited androgen receptor (AR) nuclear localization

6 , rs11 (2013)

Existing shareholders experience equity dilution when a company creates new shares, reducing their ownership percentages