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This allows us to rationalize the preference for 1,2-addition of Grignards and organolithiums as an interaction between a hard electrophile and a hard nucleophile
For example, GLP-1s are drugs that take an existing class of short-lived peptides and modify them to extend their activity duration, which turns them into drugs, following rigorous clinical testing
NLC addresses the problems of low solid lipid nanoparticles (SLN) drug load and easy drug leakage while having the slow-release advantage of SLN [51]
Bayer CropScience Journal , 61 (2), 245278
