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Results Rotarod performance and fatigue resistance To assess motor coordination and balance, VECAD IGF- 1R KD and WT mice were subjected to the rotarod test over four consecutive days

Pharmacology is well-described in peer-reviewed literature

In 2024, Sakuma et al., in Japan, carried out a clinical study to evaluate the effects of cysteine peptides, which included both reduced glutathione (GSH) and oxidized glutathione (GSSG), over 5 weeks

This strategy significantly enhanced brain-derived neurotrophic factor (BDNF) transport, achieving approximately 50% higher BBB permeability and a ~1.7-fold increase in BDNF levels in neuronal cells [60]