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Often, the basics are the real lever

Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults

Key determinants include psychological factors, lifestyle choices, cardiovascular health, and, importantly, hormonal balance

If it has a role, its more like a supporting actor than a lead therapy
