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Sublingual and intranasal routes have been proposed but lack clinical validation

They found that at six months the high-dose group showed an increase of 30-35% in GSH levels in erythrocytes, plasma and lymphocytes (and up to 260% in buccal cells) compared to baseline

The virion-incorporated Hsp70 ATPase activity and correct conformation of Hsp70-virion are essential for HIV infection, since inhibition of Hsp70 ATPase activity interrupts the Hsp70-virion core association and diminishes virus infectivity

and studies investigating the role of glutamatergic agonists to combat NMDAR hypofunction and reduce symptoms [7]