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In some cases, no reason is found

Then, -N-trimethyllysine enters mitochondria where it undergoes hydroxylation by the -N-trimethyllysine hydroxylase to produce -hydroxy-N--trimethyllysine, a process that requires vitamin C and iron as cofactors [12]

[DOI] [PubMed] [Google Scholar] 109.Paulson D.J., Schmidt M.J., Traxler J.S., Ramacci M.T., Shug A.L

At these times you may need to supplement with glutamine
