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Temozolomide induces senescence in both human and murine glioma cells and notably contributes to the accumulation of p16 INK4 positive senescent cells in mice [60, 69]
Exosomebased therapy, however, faces challenges for clinical translation
If you are low in B12, consider one or all 3 of the active B12 forms to ensure your cells have access to the most bioidentical forms available (hydroxocobalamin, adenosylcobalamin, methylcobalamin)
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