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oxidative stress can disrupt lysosomes, releasing hydrolytic enzymes and iron into the cytosol, amplifying oxidative stress and ferroptosis (66, 78)

[DOI] [PubMed] [Google Scholar] 46.Bjelakovic G., Nikolova D., Simonetti R

Clinical observations of patients have indicated that long-term exposure to high doses of propofol (surpassing 45 mgkg 1 h 1 and lasting over 48 h) can induce propofol infusion syndrome (PRIS) by damaging mitochondrial complexes II and IV in the muscles [30]
