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Subsequently, this will lead to oxidative stress, inflammatory responses, and cellular apoptosis (Li et al., 2023) Moreover, in recent studies, it was shown that PM 2.5 exposure activates the aryl hydrocarbon receptor, which in turn mediates CYP1A1 overexpression, triggering mitochondrial reactive oxygen species (ROS) generation, thus damaging the mitochondrial membrane and leading to its dysfunction (Li et al., 2023)

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Timing and dosing should be guided by clinical context

Glutathione protects immune cells from damage
