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It is critical for one simple reason: It recycles antioxidants

High-Dose Spermidine Supplementation Does Not Increase Spermidine Levels in Blood Plasma and Saliva of Healthy Adults: A Randomized Placebo-Controlled Pharmacokinetic and Metabolomic Study
It was also found that the Michaelis constant (Km = 1.2 10 5 M) of FSP1 was relatively low, and the maximum reaction rate (Vmax = 4.1 10 7 M s 1) was much higher than that of related oxidoreductases, indicating that efficiency of FSP1
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