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subtle improvements in skin hydration and texture may begin Weeks 4 to 8: Weight loss becomes measurable
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However, the high complexity of tissue microenvironments and their inherent deficiencies such as short half-live and susceptibility to enzymatic degradation, adversely affect their therapeutic efficacy and clinical applications
They are frequently investigated together because their potential mechanisms of action are thought to be complementary, creating a synergistic effect that is a popular subject of preclinical studies
