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An old in vitro study revealed that CRP hydrolysis with neutrophil-derived lysosomal enzymes yielded soluble peptides that inhibited neutrophil superoxide production, chemotaxis, degranulation, and phagocytosis [81]

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doi: 10.1038/s41371-025-00999-6 Mahmoud Khalil , Ahmed Hashim , Ahmed Maraey , Ayman Saeyeldin , Ahmed M Elzanaty , Patrick Biskupski , Kenneth Ong , Chirag R Barbhaiya , Mohamed Shokr