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A similar conclusion was obtained with the administration of 4.5 ml of a lidocaine solution on the abdomen of healthy volunteers using SC injections lasting 15 s (300 l/s), 30 s (150 l/s), and 45 s (100 l/s), with no differences in the sensation of pain between the three injection speeds [35]
Lindenbaum J, Healton EB, Savage DG, et al
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AHK-Cu Investigations into Skin Cell Research Collagen production in skin cells tends to decline with age, leading to structural weakening and decreased elasticity
