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Compared with groups A1, 2 and 3, the indices were all decreased in groups B, C and D ( P 0.05)

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Evidence has suggested that TMAO may promote inflammation via various mechanisms, including increased expression of pro-inflammatory genes (cytokine genes, IL6, TNF-, and chemokine ligands CXCL1, CXCL2) and increased pro-inflammatory effects mediated by H