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Burr cells, also known as echinocytes (or hedgehog cells), are red blood cells with a spiky or serrated outer surface, giving them a thorny appearance that contrasts with the smooth, disc-shaped profile of healthy red blood cells

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However, a recently published phase II clinical trial using the iron chelator deferiprone reported that deferiprone was ineffective in newly diagnosed PD patients who had not previously received dopaminergic therapy and even worsened both motor and non-motor symptoms [177]