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A flowchart of the article selection process is shown in Figure 3

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Distinct Cysteine residues in keap1 are required for keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress

Hence, combining the gene structure analysis with protein motifs specific to GST classes, sequence alignments and phylogenetic trees provide a robust view of the Ser-GST gene copy number present in a given organism
