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Description
5-Amino-1MQ is an NNMT inhibitor

McLean K

Zamudio J.R., Mittra B., Wohlschlegel J.A., Sturm N.R., Campbell D.A., "Trypanosoma brucei spliced leader RNA maturation by the cap 1 2'-O-ribose methyltransferase and SLA1 H/ACA snoRNA pseudouridine synthase complex", Mol Cell Biol 5: 1202-1211 (2009)

Activated microglia and astrocytes release proinflammatory cytokines, chemokines, and reactive oxygen species, contributing to synaptic dysfunction and neuronal death (Thakur et al., 2023)
