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Research data indicate that damage to both the intestinal epithelium and vascular barrier is necessary for the development of non-alcoholic steatohepatitis, which increases the role of intestinal dysbiosis in the process

Ning Q, Yang T, Guo X, Huang Y, Gao Y, Liu M, et al

[DOI] [Google Scholar] 169.Gupta B., Bchi F.N., Scherer G.G

In addition to this, there are various factors contributing to oxidative stress in FRDA, including mitochondrial labile iron, NRF2 expression, lipid peroxidation, and Ca 2+ homeostasis, which means therapeutics may need to combat a number of these factors to overcome oxidative stress