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Psychopathology, 24 (2), 53-81
Impaired Epithelial Tight Junction Protein (Occludin) mRNA and Protein Levels Are Improved by VIP Administration in DSS Mice Epithelial integrity of the colonic mucosa plays a vital role in the pathogenesis of IBD, and one major defect observed in colitis is the loss of tight junction proteins, leading to loss of barrier functions
The general goals for managing IBD are: Get rid of the symptoms of disease
Nobiletin Nobiletin, a poly-methoxy flavonoid predominantly found in citrus peels, exhibits a broad spectrum of pharmacological activities, as listed in Table 2 [191]
