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For example, Granexin Gel (containing CT1) has advanced to Phase III trial in diabetic foot ulcers, while SLI-F06, a fibromodulin-mimetic peptide hydrogel, has completed Phase I/IIa testing in post-surgical scars (Freedman et al., 2023[39])

Vitamin C helps regenerate oxidized glutathione back to its active form, allowing it to continue its antioxidant functions

Researchers using the MOTS-c 5-amino-1MQ stack protocol often take 5-amino-1MQ in the morning alongside their first MOTS-c injection, or alternatively, dose it in the evening to extend the NAD+ elevation window across the full 24-hour period

The study was approved by the Local Ethics Committee at School of Medicine (University of Zagreb, Zagreb, Croatia) and experiments were assessed by observers unaware of the given treatment