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doi: 10.1038/s41586-018-0620-2 4 NakamotoNSasakiNAokiRMiyamotoKSudaWTerataniTet al

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In addition, oxidative stress inhibits the peroxiredoxin 1 (Prx1) redox-regulated protein in 661W cells

Free radicals and other factors, including radiation, sun exposure, and pollution, can worsen under-eye black circles
