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Semax: A Scientific Perspective on a Neuropeptide in the Context of Contemporary Research Semax is a synthetic neuropeptide derived from ACTH that has attracted scientific interest for its potential role in neuroplasticity, neurotrophic factor regulation, and neural signaling

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However, it is essential to note that sustained elevation in plasma glucose concentrations due to reduced pancreatic insulin release from chronic melatonin treatment, especially when extending beyond the sleeping period [140], may compromise melatonins potential to ameliorate AD pathology [141, 142]