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10.1038/s41598-023-38134-5 3 AlshabiA

For instance, tissue apical exposure to Chlorocresol failed to induce a CBF decrease in MucilAir-HF tissues, and LPS via apical exposure did not trigger intense inflammatory cytokine secretion in EpiAveolar model, whereas a mild response was observed in MucilAir-HF tissues exposed to TNF- and LPS (at 6h/day aerosol exposure only)

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These findings suggest that HRW has potential as a therapeutic strategy for AD by targeting oxidative stress, inflammation, and gut-brain axis modulation
