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However, there has been less emphasis on thiazide-like diuretics, despite evidence that both chlorthalidone and indapamide may offer better metabolic outcomes compared to hydrochlorothiazide (Kostis et al., 1997

At the cellular level, UVB induces keratinocytes to release endothelin-1, which leads to a downregulation of E-cadherin expression in melanocytes, thereby disrupting their adhesion and intercellular communication 20,21

Psychiatry 18, 369381

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