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However, there has been less emphasis on thiazide-like diuretics, despite evidence that both chlorthalidone and indapamide may offer better metabolic outcomes compared to hydrochlorothiazide (Kostis et al., 1997

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At the cellular level, UVB induces keratinocytes to release endothelin-1, which leads to a downregulation of E-cadherin expression in melanocytes, thereby disrupting their adhesion and intercellular communication 20,21

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Psychiatry 18, 369381

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