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Description
Preclinical data presented in a conference abstract demonstrated AG-946's ability to normalize levels of glycolytic intermediates, decrease 2,3-DPG levels, and increase hemoglobin levels in a Townes HbSS mouse model, although it did not significantly affect ATP levels or degree of RBC sickling

But, people with this condition should talk to their doctor before taking B12 supplements

doi: 10.3389/fphys.2014.00152 77 EgertonS.CullotyS.WhooleyJ.StantonC.RossR

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