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Tagore S., Caprio L., Amin A

A network pharmacology study revealed that HSYA can inhibit PASMC proliferation and PVR and reduce pulmonary arterial wall thickness and muscularization by modulating genes such as ANXA5, SRC, PGR, EGFR, PPARG, and ESR1, thereby improving HPH

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The link between the reduction of autophagy and mTORC1 pathway activation was demonstrated by the increase of S6K phosphorylation in vitiligo melanocytes after treatment with NAC, as revealed through immunofluorescence analysis and quantitative measurement of the staining intensity (Fig
