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It is worth noting that thiostreptozotocin promotes ferroptosis by downregulating GPX4 mRNA and GPX levels mainly by decreasing intracellular STAT3 and p-STAT3 expression rather than affecting SLC7A11 protein expression [140]
Nanotechnology meets atopic dermatitis: current solutions, challenges and future prospects

Oxidative stress, which is resulted from an imbalance between the production of free radicals and the ability of antioxidant defense mechanism to deactivate them, is involved in the development of many chronic diseases such as cancer, diabetes, CVD and some neurodegenerative diseases

S.PogginM.et al (2008)
