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L-type Ca 2+ channels (LTCCs) facilitate Ca 2+ influx during late myocyte depolarization, provoking the Ca 2+ -induced Ca 2+ release that sustains the action potential plateau and catalyzes myofilament interaction (Wu and Corr, 1992
L-Carnitine is an amino acid derivative and a powerful supplement that shuttles nutrients into mitochondria and cranks up energy production in the cells
We propose that the underlying mechanism behind that impact may be related to the mitigation of cellular oxidative damage and glycolipotoxicity, according to previous evidence from preclinical and clinical studies