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( f-g ) Cells were treated with the IDH1 inhibitor ( f ) or cultured under glutamine starvation ( g ) and treated cisplatin (Cis) alone and in combination with or without l-carnitine supplementation (n = 4 technical replicates representative from 3 independent experiments)
Am J Physiol Endocrinol Metab (2020) 318:E52537
reported that GLS inhibition preferentially radiosensitizes KEAP1-mutant non-small cell lung cancer cells via depletion of GSH and enhanced DNA damage [75]
Several investigations also found that changing ones lifestyle to include exercise can significantly lower TMAO levels [112]
