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Continuous data collected from the participants over the 26 week treatment period was assessed using an ANCOVA model, using randomized treatment as a factor and baseline bodyweight as a covariate

While NPPC-centered therapy holds substantial potential for mitigating IDD, translating this promise into effective clinical treatments requires overcoming major translational challenges

Beyond scientific interest, these findings have translational relevance, as modulating adipocyte function or addressing eating behaviors could serve as potential targets for adjunctive therapies in MM (95, 101)