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Anti-ferroptotic genes and lipid metabolism genes are highlighted

It is difficult to judge for sure whether the early drastic decrease in Plp- and Mog- positive cells implies a drastic death/loss of the mature OLs or just an extreme-down regulation of the expression of these myelin-associated genes by the OLs while they themselves are still alive

Analytical Concentration: In-vitro assays typically utilise a range of 1 nM to 10 M to establish combined pathway metrics

However, by 3 months, the cumulative effect of curcumin resulted in significant reductions in both Visual Analogue Scale pain at rest and during activity, when compared to the baseline and the placebo group