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Recent advances, primarily based on three landmark clinical studies, namely, Nix-TB, ZeNix, and TB PRACTECAL (Nyangwa et al., 2022), led to the introduction of 69 months regimens of bedaquiline, pretomanid, linezolid, with or without moxifloxacin (BPaL-M or BPaL, respectively), offering improved outcomes compared to older treatment strategies (Johnson et al., 2024)
No evidence was found that EGCG/AA NPs utilized a specific pathway across the blood-brain barrier (BBB)
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