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With the discovery and approval of new, more tolerable antibiotics, colistin, like the other polymyxins, was gradually dismissed from clinical use due to the high incidence of nephrotoxicity

Theres a meaningful preclinical body of work from one lab, a striking in vitro potency finding that drove a decade of nootropic hype, and almost no human clinical evidence

Processing of X-ray diffraction data collected in oscillation mode