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Copper overload: Theoretically possible with high-dose systemic use, though not documented at typical topical concentrations

ROS are usually present in the form of superoxide anion, hyphochlorous acid, hydrogen peroxide, singlet oxygen, hypochlorite, hydroxyl radical, and lipid peroxides, which are produced during cells progression, growth, death, and differentiation [9]

10.1152/ajpheart.1996.270.5.H1803 99

Pregnancy & Breastfeeding The data just isn't there yet
