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Description
The degenerative process of intervertebral discs is often accompanied by the overexpression of matrix metalloproteinases (MMP3, MMP13) and inflammatory factors (IL-1, IL-6, IL-8, PEG2, TNF-) (Wang et al., 2020)
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Importantly, the processes described here apply mainly to the production and metabolism of dopamine in the CNS as mediated by dopaminergic neurons
