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doi: 10.1016/j.neulet.2020.134919
l-2HG production was achieved by glutarate hydroxylase extending lysine biosynthesis in a six-step cascade, in which only the last committed step catalyzed by oxygen-dependent glutarate hydroxylase requires oxygen
demonstrated that GSTZ1 downregulation resulted in decreased GSH and elevated ROS levels, which activated NRF2-associated pathways (94)
Glutathione is a powerful antioxidant that your body produces
