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Other candidates include people who've experienced nerve damage from nitrous oxide exposure (sometimes called "laughing gas neuropathy") and those battling unexplained fatigue or neurological symptoms that haven't responded to other treatments

that compliance and monitoring are better in patients who receive this form of therapy because they have frequent contact with health care providers, whereas proponents of oral therapy maintain that compliance will be improved in patients who receive oral therapy because of convenience, comfort, and decreased expense

So this article does two things at once

found that NNMT expression in adipocytes is increased in Pima Indians [27]