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Zadik Z, Chalew SA, McCarter RJ, Jr., Meistas M, Kowarski AA

However, a recent randomized, double-blind, controlled study, performed in 60 healthy postmenopausal women conclude that while there was a E2 decrease when giving anastrozole (an inhibitor of aromatase activity), but no changes in E2 levels were observed when fulvestrant (a selective estrogen receptor- antagonist) was administered

And thats something that happens as well because visceral fat is surrounding the liver

It functions as a cofactor for lysyl oxidase (the enzyme responsible for collagen cross-linking and stabilization), ceruloplasmin (a copper transport protein with antioxidant activity), and superoxide dismutase (SOD, a primary antioxidant defense enzyme)