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Effects of melatonin supplementation on hormonal, inflammatory, genetic, and oxidative stress parameters in women with polycystic ovary syndrome

Furthermore, the combination of metabolomics with in vitro models represents a great step forward in the use of human-relevant non-animal alternatives in toxicology

NRF2 regulating the antioxidant stress response NRF2 is a crucial nuclear transcription factor that plays a key role in cellular antioxidant defense and protection

But when free radicals outnumber antioxidant defenses, it leads to a process called oxidative stress, linked with inflammation, impaired immunity and serious health concerns