gpx4 glutathione Selective Small-Molecule Activator of Patient-Derived Variant Validated by Unraveling the Role of GPX4

Contaminated products have been documented to cause reputational harm and substantial economic losses for athletes

doi: 10.1038/s41572-025-00594-6 10 WangZShiWWuLXiaoYWangMZhangSet al

Cross resistance can occur between insecticides from different chemical classes

To critically appraise mechanisms and levels of evidence ( in vitro, in vivo , clinical) for vitamin E and C, glutathione and its precursors, polyphenols (quercetin, resveratrol, curcumin), Crocus sativus carotenoids (crocin/safranal), and indirect modulators (e.g., omega-3, folinic acid), emphasizing study quality, translational relevance, and limitations