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Desoye, G
The ryanodine receptor is involved in release of Ca 2+ from the SR so, although it is evident that SELENON loss results in impairment of Ca 2+ homeostasis, the origin of this defect remains unclear and may involve both the release (ryanodine receptor) and re-uptake (SERCA) of Ca 2+
10.1016/j.clinbiochem.2007.01.012 Clin Biochem
Owing to its exclusive activity towards reduced glutathione, ChaC1 upregulation results in not only glutathione depletion but in alterations in cellular redox ratios (47)
