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van der Windt, G
Annu Rev Plant Physiol Plant Mol Biol 52:437467 Smirnoff N, Wheeler GL (2000) Ascorbic acid in plants: biosynthesis and function

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Demonstrated that systemic injections of cartilage-targeted IGF-1 fusion proteins had direct effects on the growth plate without off-target effects on the kidney that are seen with normal IGF-1
