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IFN can form an important anti-ferroptosis system with SLC3A2 ( 6.5 Ferroptosis and cuproptosis Cuproptosis is defined as the aggregation of proteins, proteotoxic stress, and eventual cell death triggered by copper binding to the lipolytic enzymes of the tricarboxylic acid (TCA) cycle

Therefore, with the deepening of research, the regulatory pathways of ferroptosis in the antioxidant system are not limited to GSH-dependent antioxidant pathways, but also can play a role in regulating ferroptosis through GSH-independent antioxidant pathways, which means that there may be more regulatory mechanisms related to ferroptosis waiting for us to further explore

Modulation of certain immunologic responses by vitamin C