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Interferon-gamma (IFN-) was found to augment CD1d expression on keratinocytes, leading to their activation and the subsequent stimulation of NKT cells

In particular, DCA is known for its ability to promote inflammation, kill bacteria, and trigger increased secretion in the colon [42, 43]

Sphingomyelins, in particular, are hypothesized to play a critical role in skeletal muscle function, potentially impacting muscle fatigue (Sabbadini et al., 2016)

This comprehensive review brings together multiple lines of evidence for the dysfunction of the glutamate system in mood disorders, including genetic, post-mortem and in vivo neuroimaging data