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As of the writing of this Special Report, such tests are limited to use in specialty care clinics to aid in the diagnostic workup of symptomatic individuals and are still being validated in clinical trials

Exposure of RAW 264.7 cells to LPS for four hours dramatically increased the secretion of IL-6 to 613.2 35.1 pg/ml and TNF- to 1556.3 23.3 pg/ml

Conclusions The concept of the leaky gut, although used to explain the pathogenesis of many common diseases, should be rethought in terms of the available data that support the many means by which luminal substances cross the gut mucosal barrier

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