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The PGC-1/NRF1 axis is critical for the regulation of Fundc1 expression, as evidenced by both the direct binding of NRF1 and PGC-1 to the Fundc1 promoter and the stimulation of FUNDC1 protein production by PGC-1 overexpression [230]

The samples were pooled into libraries and sequenced on the Illumina NovaSeq 6000 at a minimum depth of 20,000 reads per cell

An earlier LEGEND Hypertension study, published in The Lancet, found that thiazide diuretics were more effective and caused fewer side effects than ACE inhibitors when used as first-line antihypertensive drugs

Acetaldehyde production by brain homogenates from CYP2E1-null mice was not affected by the absence of CYP2E1 (Vasiliou, Ziegler et al